Hox patterning of the vertebrate rib cage

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Hox patterning of the vertebrate rib cage.

Unlike the rest of the axial skeleton, which develops solely from somitic mesoderm, patterning of the rib cage is complicated by its derivation from two distinct tissues. The thoracic skeleton is derived from both somitic mesoderm, which forms the vertebral bodies and ribs, and from lateral plate mesoderm, which forms the sternum. By generating mouse mutants in Hox5, Hox6 and Hox9 paralogous gr...

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Hox patterning of the vertebrate axial skeleton.

The axial skeleton in all vertebrates is composed of similar components that extend from anterior to posterior along the body axis: the occipital skull bones and cervical, thoracic, lumbar, sacral, and caudal vertebrae. Despite significant changes in the number and size of these elements during evolution, the basic character of these anatomical elements, as well as the order in which they appea...

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Collinear Hox-Hox interactions are involved in patterning the vertebrate anteroposterior (A-P) axis

Investigating regulation and function of the Hox genes, key regulators of positional identity in the embryo, opened a new vista in developmental biology. One of their most striking features is collinearity: the temporal and spatial orders of expression of these clustered genes each match their 3' to 5' order on the chromosome. Despite recent progress, the mechanisms underlying collinearity are ...

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The Effects of Rib Cage Compression before endotracheal suctioning

Abstract Introduction: Accumulation of secretions in airways is a serious complication in intubated and mechanically ventilated patients. Tracheal suctioning which is done with the aim of secretion removal can be used in conjunction with physiotherapy for effective airway clearance and improving gas exchange. Objective: The aim of study was to determine the effects of rib cage compression befor...

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ژورنال

عنوان ژورنال: Development

سال: 2007

ISSN: 1477-9129,0950-1991

DOI: 10.1242/dev.007567